All times listed are cst.

Wednesday, December 9:  Single Molecule Techniques

9:00                Welcome  – John Tainer, MD Anderson Cancer Center and Jane Tao, Rice University

Convener:     Michael Zhu, University of Texas Health Science Center Houston

9:05             Keynote Speaker
Unraveling the Specificity and Inhibition of CRISPR-Cas Nucleases
Ilya Finkelstein, University of Texas Austin

9:45                Glutamate Receptors are the Single Molecule Level
Vasanthi Jayaraman, University of Texas Health Science Center Houston

 10:15               Trainee Talk
Structural Interrogation of Enzymes Involved in the Biosynthesis of Enediyne Natural Products
Abigael Kosgei, Rice University

10:25              Break

Convener:  Ching-Hwa Kiang, Rice University

10:40              Keynote Speaker
Cohesin SA1 and SA2 are RNA Binding Proteins that Localize to RNA Containing Regions on DNA
Hong Wang, North Carolina State University

11:20              3D Single-molecule Super-resolution Light Sheet Imaging Throughout Mammalian Cells
Anna-Karin Gustavsson, Rice University

11:50              Trainee Talk
Long-range Coupled Motions Underlie Ligand Recognition by a Chemokine Receptor
Vinay Nair, University of Texas Health Science Center Houston

12:00-12:40 pm  Poster Session 1

Thursday, December 10: Computational Modeling

Convener:     Jim Briggs, Univeristy of Houston

9:00                Drugging KRAS with Allosteric Non-covalent Inhibitors
Alex Gorfe, University of Texas Health Science Center Houston

:30                Keynote Speaker
Harnessing the Power of Whole Genome Sequencing in Analysis of Mutagenesis in Human Cells
Serena Nik-Zainal, University of Cambridge

 10:10  Break

Convener:     Jianpeng Ma, University of Houston

10:20              De Novo Modeling Building in CryoEM Density Maps
Matt Baker, University of Texas Health Science Center Houston

11:00              Keynote Speaker
The Coming of Age of De Novo Protein Design
David Baker, University of Washington

Convener:     Jim Briggs, University of Houston

11:40              Trainee Talk
Exploring the Energy Landscape of Chromosomes: Transitions Between Interphase and Mitotic Phase
Vinícius Contessoto, Rice University and São Paulo State University

11:50              Trainee Talk
Cryo-EM Reconstruction of a Covalently Linked Viral Fiber                        Jim Zhang, Rice University

12:00-12:40 pm  Poster Session 2

Friday, December 11: CryoEM, CryoTM and MicroED

Convener:     Yimo Han, Rice University

9:00              Keynote Speaker
                        MicroED: Conception, Practice and Future Opportunities
Tamir Gonen, University of California Los Angeles

9:40                Cryo-EM Analysis of IP3R Channel in a Lipid Bilayer
Mariah Baker, University of Texas Health Science Center Houston

 10:20              Break

Convener:     Ming Zhou, Baylor College of Medicine

10:30              Keynote Speaker
Structure, Dynamics and Interactions in the Regulation of Macromolecular Function Studied by Cryo-EM
Eva Nogales, Lawrence Berkeley National Lab

11:10              CryoET for In-situ Structure and Dynamics at Subnanometer Resolution
Steve Ludtke, Baylor College of Medicine

11:40              A Viral Genome Packaging Motor Transitions Between Cyclic and Helical Symmetry to Translocate dsDNA
Marc Morais, University of Texas Medical Branch at Galveston